Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346989 | 0.94 | ESR1 (0.44) | ESR1ESR2ITGA4ENPP3 | |
| SCHEMBL7352553 | 0.90 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL7352615 | 0.87 | ITGA4 (0.45) | ESR1ESR2ITGA4SRCFLT3 | |
| SCHEMBL7438752 | 0.84 | ESR1 (0.49) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL7349173 | 0.81 | ESR1 (0.55) | ESR1ESR2 | |
| SCHEMBL7347006 | 0.78 | ITGA4 (0.53) | ESR1ESR2ITGA4SRC | |
| SCHEMBL7348137 | 0.76 | ESR1 (0.55) | ESR1ESR2ENPP3 | |
| SCHEMBL7347763 | 0.75 | ESR1 (0.49) | ESR1ESR2ENPP3ENPP1 | |
| SCHEMBL7350932 | 0.73 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL7772332 | 0.70 | ESR1 (0.74) | ESR1ESR2ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997460-B1 | Benzothiophene compounds as antithrombotic agents and intermediates | LILLY CO ELI (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6133262-A | 3-AMINOBENZO(B)THIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0997460-A1 | Benzothiophene compounds as antithrombotic agents and intermediates | ELI LILLY AND COMPANY (US) | 2000-05-03 | — | — | EP | disclosed |