Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334481 | 0.85 | POLB (0.84) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL10914671 | 0.85 | ALDH1A1 (0.64) | POLBALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL10447618 | 0.85 | ALDH1A1 (0.70) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL11025208 | 0.84 | POLB (0.68) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL15303789 | 0.82 | KDM4E (0.83) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10334554 | 0.81 | KDM4E (0.81) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL11847732 | 0.81 | KDM4E (0.76) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL14076355 | 0.80 | POLB (0.97) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL27535462 | 0.79 | POLB (0.74) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 | |
| Propionic Acid SCHEMBL9781843 | 0.79 | POLB (0.65) | POLBALDH1A1CYP1A2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514401-A | CARDIOTONICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |