Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 15/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354424 | 0.92 | CACNA1B (0.57) | CACNA1B | |
| SCHEMBL7355814 | 0.91 | CACNA1B (0.60) | CACNA1BCCR5 | |
| SCHEMBL7383462 | 0.91 | CACNA1B (0.64) | CACNA1BKDM4ECCR5ALDH1A1 | |
| SCHEMBL7354602 | 0.90 | CACNA1B (0.53) | CACNA1B | |
| SCHEMBL7355681 | 0.89 | CACNA1B (0.62) | CACNA1BKDM4ECCR5ALDH1A1LMNA | |
| SCHEMBL7349612 | 0.88 | CACNA1B (0.67) | CACNA1BKDM4ECCR5ALDH1A1LMNA | |
| SCHEMBL7040882 | 0.87 | CACNA1B (0.73) | CACNA1BCCR5LMNA | |
| SCHEMBL7041837 | 0.87 | CACNA1B (0.73) | CACNA1BCCR5LMNA | |
| SCHEMBL7040887 | 0.87 | CACNA1B (0.73) | CACNA1BCCR5LMNA | |
| SCHEMBL7355754 | 0.87 | CACNA1B (0.54) | CACNA1BCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |