Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 15/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348102 | 0.91 | CACNA1B (0.68) | CACNA1BALDH1A1KDM4ECCR5 | |
| SCHEMBL7355681 | 0.90 | CACNA1B (0.62) | CACNA1BALDH1A1KDM4ECCR5 | |
| SCHEMBL7349612 | 0.89 | CACNA1B (0.67) | CACNA1BNPC1MEN1ALDH1A1TP53 | |
| SCHEMBL7349589 | 0.86 | CACNA1B (0.69) | CACNA1BPOLBL3MBTL1NPC1MEN1 | |
| SCHEMBL7040887 | 0.84 | CACNA1B (0.73) | CACNA1BPOLBL3MBTL1NPC1CCR5 | |
| SCHEMBL7040882 | 0.84 | CACNA1B (0.73) | CACNA1BPOLBL3MBTL1NPC1CCR5 | |
| SCHEMBL7041837 | 0.84 | CACNA1B (0.73) | CACNA1BPOLBL3MBTL1NPC1CCR5 | |
| SCHEMBL7392965 | 0.84 | CACNA1B (0.66) | CACNA1BNPC1MEN1ALDH1A1TP53 | |
| SCHEMBL7383572 | 0.84 | CACNA1B (0.43) | CACNA1BALDH1A1KMT2A | |
| SCHEMBL7350421 | 0.83 | CACNA1B (0.54) | CACNA1BNPC1MEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |