⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29526750 | 0.77 | — | — | |
| SCHEMBL24420456 | 0.77 | — | — | |
| SCHEMBL38664613 | 0.77 | LMNA (0.38) | — | |
| SCHEMBL1132433 | 0.74 | — | — | |
| SCHEMBL2605772 | 0.74 | CYP17A1 (0.36) | — | |
| SCHEMBL16822027 | 0.74 | AOC3 (0.38) | — | |
| SCHEMBL24592341 | 0.74 | — | — | |
| SCHEMBL371953 | 0.73 | — | — | |
| SCHEMBL7995657 | 0.73 | — | — | |
| SCHEMBL24097115 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185465-B | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-113185465-A | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113185465-B | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113185465-B | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113185465-B | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113185465-A | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113185465-A | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113185465-A | Preparation method of 4-ethyl-5-aminopyrimidine | 无锡捷化医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20210111355-A1 | Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues | UNIV ARIZONA STATE (US) | 2021-04-15 | — | — | US | disclosed |
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20180148464-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-31 | — | — | US | disclosed |
| US-20130217664-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2013-08-22 | — | — | US | disclosed |
| WO-2013117645-A1 | IMIDAZO [4, 5 -C] PYRIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2013-08-15 | — | — | WO | disclosed |
| WO-2013117649-A1 | IMIDAZO [4, 5 -C] PYRIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2013-08-15 | — | — | WO | disclosed |
| WO-2013117649-A1 | IMIDAZO [4, 5 -C] PYRIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2013-08-15 | — | — | WO | disclosed |
| WO-2013117645-A1 | IMIDAZO [4, 5 -C] PYRIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2013-08-15 | — | — | WO | disclosed |
| US-20130178455-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC (US) | 2013-07-11 | — | — | US | disclosed |
| US-8329684-B2 | Cephalosporin derivatives and pharmaceutical compositions thereof | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-12-11 | — | — | US | disclosed |
| US-20120264727-A1 | NOVEL CEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LEGOCHEM BIOSCIENCES, INC. (KR) | 2012-10-18 | — | — | US | disclosed |
| US-5318975-A | 5-pyrimdineamine derivatives | BERLEX LABORATORIES, INC. (US) | 1994-06-07 | — | — | US | disclosed |