Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | CPA1 | P15085 | 4/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310740 | 0.83 | MME (0.48) | MMEACECPA1ACE2 | |
| SCHEMBL7310766 | 0.83 | MME (0.48) | MMEACECPA1ACE2 | |
| SCHEMBL7407171 | 0.82 | MME (0.50) | MMEACECPA1ACE2 | |
| SCHEMBL7407179 | 0.82 | MME (0.50) | MMEACECPA1ACE2 | |
| SCHEMBL7309981 | 0.81 | MMEL1 (0.59) | MMEACE | |
| SCHEMBL7314989 | 0.79 | MMEL1 (0.51) | L3MBTL1 | |
| SCHEMBL7314730 | 0.79 | MMEL1 (0.54) | MMEACEL3MBTL1 | |
| SCHEMBL7340639 | 0.78 | MMEL1 (0.55) | MMEACE | |
| SCHEMBL7309974 | 0.78 | MMEL1 (0.55) | MMEACE | |
| SCHEMBL7320015 | 0.78 | MMEL1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |