SCHEMBL7348251

SCHEMBL7348251

CC[C@@H](CNC(=O)C(Cc1ccc(-c2ccccc2)cc1)N(c1ccccc1)C(c1ccccc1)P(=O)(O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.41
MME P08473 3/20 0.41
ANPEP P15144 2/20 0.41
PPARG P37231 2/20 0.39
ACE P12821 1/20 0.39
CPA1 P15085 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310771 0.84 ACP3 (0.46) ACP3MMEACE
SCHEMBL7312217 0.82 MMEL1 (0.55) ACP3
SCHEMBL7310813 0.82 MMEL1 (0.55) ACP3
SCHEMBL7309986 0.82 MMEL1 (0.55) ACP3
SCHEMBL7314996 0.81 MMEL1 (0.47) ACP3
SCHEMBL7314736 0.79 MMEL1 (0.48) MMEACE
SCHEMBL7320018 0.79 MMEL1 (0.46) ACP3
SCHEMBL7318929 0.79 MMEL1 (0.50)
SCHEMBL7340648 0.77 MMEL1 (0.48) MMEACE
SCHEMBL7309977 0.77 MMEL1 (0.48) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592367-A2 Phosphono/biaryl substituted dipeptide derivatives CIBA-GEIGY AG (CH) 1994-04-13 EP disclosed