Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673018 | 0.93 | CYP2C9 (0.68) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL7342557 | 0.88 | HSD17B10 (0.66) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL7344861 | 0.88 | HSD17B10 (0.66) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL5474815 | 0.87 | ABCB11 (0.67) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL4986252 | 0.86 | TBXA2R (0.75) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL3185862 | 0.86 | TBXA2R (0.75) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL31473037 | 0.86 | TBXA2R (0.75) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL9673483 | 0.86 | HSD17B10 (0.63) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL7350118 | 0.86 | HSD17B10 (0.61) | HSD17B10KDM4ECYP2C9TBXA2RADRA1A | |
| SCHEMBL7347116 | 0.86 | HSD17B10 (0.56) | HSD17B10CYP2C9ADRA1ASLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |