Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 2/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338728 | 0.80 | CYP1A2 (0.50) | KMT2ACYP1A2CYP2D6MEN1DRD4 | |
| SCHEMBL23121057 | 0.79 | CYP1A2 (0.70) | CYP1A2CYP2D6DRD4ALDH1A1 | |
| SCHEMBL7344285 | 0.77 | CYP2D6 (0.47) | KMT2ACYP1A2CYP2D6DRD4 | |
| SCHEMBL7339944 | 0.76 | CYP1A2 (0.36) | CYP1A2CYP2D6DRD4ACHE | |
| SCHEMBL10690989 | 0.74 | CYP1A2 (0.67) | KMT2ACYP1A2CYP2D6MEN1DRD4 | |
| SCHEMBL7339633 | 0.74 | CYP1A2 (0.46) | KMT2ACYP1A2CYP2D6MEN1DRD4 | |
| SCHEMBL515999 | 0.74 | G6PC1 (0.54) | KMT2ACYP1A2CYP2D6MEN1RAB9A | |
| SCHEMBL28410816 | 0.74 | G6PC1 (0.54) | KMT2ACYP1A2CYP2D6MEN1RAB9A | |
| SCHEMBL7885548 | 0.74 | G6PC1 (0.54) | KMT2ACYP1A2CYP2D6MEN1RAB9A | |
| SCHEMBL3373703 | 0.73 | KMT2A (0.67) | KMT2AMEN1RAB9ADRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598962-B1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH AS (DK) | 1999-02-17 | — | — | EP | claimed |
| EP-0598962-A1 | Imidazole derivatives as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-06-01 | — | — | EP | disclosed |
| US-5296493-A | Analgesics or antiischemics | NEUROSEARCH A/S (DK) | 1994-03-22 | — | — | US | disclosed |