Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381058 | 0.82 | KMT2A (0.56) | CYP2D6 | |
| SCHEMBL3066938 | 0.80 | — | — | |
| SCHEMBL8962578 | 0.80 | CYP2D6 (0.53) | CYP2D6 | |
| SCHEMBL124180 | 0.78 | CYP2D6 (0.51) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL10550374 | 0.78 | — | — | |
| SCHEMBL9645566 | 0.78 | HTT (0.59) | — | |
| SCHEMBL7063746 | 0.78 | CYP2D6 (0.48) | CYP2D6 | |
| SCHEMBL11145478 | 0.72 | CYP2D6 (0.46) | CYP2D6 | |
| SCHEMBL2245340 | 0.72 | CYP2D6 (0.44) | CYP2D6 | |
| SCHEMBL283340 | 0.72 | CYP2D6 (0.44) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156318-A2 | C-terminal amide cyclic renin inhibitors containing peptide isosteres | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | disclosed |