⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2487756 | 1.00 | — | — | |
| SCHEMBL14716928 | 0.94 | CARM1 (0.47) | — | |
| SCHEMBL5425 | 0.94 | — | — | |
| SCHEMBL31726679 | 0.89 | — | — | |
| Iodide SCHEMBL7118709 | 0.89 | — | — | |
| SCHEMBL1393802 | 0.89 | — | — | |
| Bromide SCHEMBL7115005 | 0.89 | — | — | |
| SCHEMBL29755267 | 0.89 | — | — | |
| SCHEMBL31327263 | 0.89 | — | — | |
| SCHEMBL30273045 | 0.89 | CARM1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |