Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.65 |
| ▸ | CTRC | Q99895 | 2/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348910 | 1.00 | CMA1 (0.65) | CMA1CTRCKLK5ELANEF2 | |
| SCHEMBL7354560 | 0.93 | KLK5 (0.59) | CMA1CTRCKLK5F2 | |
| SCHEMBL7354569 | 0.93 | KLK5 (0.59) | CMA1CTRCKLK5F2 | |
| SCHEMBL7352303 | 0.90 | F2 (0.59) | CMA1CTRCKLK5F2 | |
| SCHEMBL7352316 | 0.90 | F2 (0.59) | CMA1CTRCKLK5F2 | |
| SCHEMBL7348799 | 0.89 | MAPK1 (0.55) | CMA1KLK5F2 | |
| SCHEMBL7348789 | 0.89 | MAPK1 (0.55) | CMA1KLK5F2 | |
| SCHEMBL4455011 | 0.84 | CMA1 (0.73) | CMA1CTRCELANE | |
| SCHEMBL7381855 | 0.83 | KLK5 (0.53) | CMA1KLK5F2 | |
| SCHEMBL7381848 | 0.83 | KLK5 (0.53) | CMA1KLK5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |