Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.52 |
| ▸ | MMP9 | P14780 | 10/20 | 0.52 |
| ▸ | MMP13 | P45452 | 10/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352386 | 0.93 | MMP1 (0.52) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7349012 | 0.93 | MMP1 (0.46) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7402860 | 0.92 | MMP1 (0.51) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7350596 | 0.92 | MMP1 (0.54) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7355972 | 0.90 | MMP1 (0.66) | MMP1MMP9MMP13 | |
| SCHEMBL7347888 | 0.85 | MMP1 (0.45) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7411808 | 0.84 | MMP1 (0.46) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7349184 | 0.84 | MMP1 (0.49) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7348309 | 0.84 | MMP1 (0.51) | MMP1MMP9MMP13CHEK2 | |
| SCHEMBL7354333 | 0.83 | CHEK2 (0.38) | MMP1MMP9MMP13ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970046-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998038163-A1 | N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |