Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17838938 | 0.85 | CSNK1A1 (0.57) | CSNK1A1CLK4NPC1RAB9AMEN1 | |
| SCHEMBL979231 | 0.80 | CSNK1A1 (0.92) | CSNK1A1CLK4ADORA2AADORA1CYP2D6 | |
| SCHEMBL2326954 | 0.80 | CSNK1A1 (0.66) | CSNK1A1CLK4NPSR1ADORA2AADORA1 | |
| SCHEMBL3929311 | 0.80 | ADORA2A (0.62) | CSNK1A1CLK4NPC1RAB9AMEN1 | |
| SCHEMBL6492186 | 0.79 | CSNK1A1 (0.55) | CSNK1A1CLK4NPC1RAB9AADORA2A | |
| SCHEMBL2323073 | 0.79 | ADORA2A (0.79) | CSNK1A1CLK4ADORA2AADORA1ADORA2B | |
| SCHEMBL30186651 | 0.79 | ADORA2A (0.79) | CSNK1A1CLK4ADORA2AADORA1ADORA2B | |
| SCHEMBL976667 | 0.79 | CSNK1A1 (1.00) | CSNK1A1CLK4ADORA2AADORA1CYP2D6 | |
| SCHEMBL12922467 | 0.78 | CSNK1A1 (0.63) | CSNK1A1CLK4NPC1RAB9AMEN1 | |
| SCHEMBL975779 | 0.78 | CSNK1A1 (0.53) | CSNK1A1CLK4NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329521-B2 | Process for preparing substituted benzoyl cyanide amidinohydrazones | CHEMAGIS, LTD. (IL) | 2001-12-11 | — | — | US | disclosed |
| US-20010025118-A1 | Process for preparing substituted benzoyl cyanide amidinohydrazones | CHEMAGIS LTD. (IL) | 2001-09-27 | — | — | US | disclosed |
| EP-1127873-A2 | Process for preparing substituted Benzoyl Cyanide Amidinohydrazones | Chemagis Ltd. (IL) | 2001-08-29 | — | — | EP | disclosed |
| US-4602017-A | Substituted aromatic compounds | SMITHKLINE BEECHAM CORPORATION(A PENNSYLVANIA CORPORATION) | 1986-07-22 | — | — | US | disclosed |
| EP-0064158-A1 | Omega-cyano-1, omega-diphenyl azalcane derivatives, their preparation and pharmaceutical preparations containing them | BASF Aktiengesellschaft (DE) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025118-A1 | Process for preparing substituted benzoyl cyanide amidinohydrazones | SLC6A19, CPS1, SLC1A5 | CSNK1A1 1672/4885CLK4 3931/4885NPC1 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.