Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358061 | 1.00 | ACE (0.52) | ACETBXAS1ALDH1A1 | |
| SCHEMBL11075923 | 0.84 | ACE (0.69) | ACETBXAS1 | |
| SCHEMBL7350842 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL11165043 | 0.77 | ACE (0.55) | ACETBXAS1 | |
| SCHEMBL7321116 | 0.77 | CYP1A2 (0.43) | ALDH1A1 | |
| SCHEMBL11078981 | 0.76 | ACE (0.52) | ACETBXAS1 | |
| SCHEMBL7356184 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7363795 | 0.76 | ACE (0.57) | ACE | |
| SCHEMBL11072970 | 0.74 | ACE (0.59) | ACE | |
| SCHEMBL11072211 | 0.73 | ACE (0.51) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |