Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.64 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.57 |
| ▸ | OXTR | P30559 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353229 | 0.89 | AVPR1A (0.68) | AVPR1AAVPR2OXTRPOLB | |
| SCHEMBL7350006 | 0.86 | ALDH1A1 (0.68) | AVPR1AAVPR2OXTR | |
| SCHEMBL5237261 | 0.86 | AVPR2 (0.76) | AVPR1AAVPR2OXTR | |
| SCHEMBL7352032 | 0.83 | AVPR1A (0.62) | AVPR1AAVPR2OXTR | |
| SCHEMBL7352676 | 0.83 | ALDH1A1 (0.61) | AVPR1AAVPR2OXTR | |
| SCHEMBL7346963 | 0.82 | AVPR1A (0.73) | AVPR1AAVPR2OXTR | |
| SCHEMBL7349433 | 0.80 | AVPR1A (0.70) | AVPR1AAVPR2OXTR | |
| SCHEMBL7345957 | 0.80 | AVPR1A (0.70) | AVPR1AAVPR2OXTR | |
| SCHEMBL7343792 | 0.80 | AVPR1A (0.61) | AVPR1AAVPR2OXTRPOLB | |
| SCHEMBL7346948 | 0.80 | AVPR1A (0.64) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |