Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341927 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL7349391 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL7342954 | 0.93 | ITGB3 (0.53) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL7343777 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL7343127 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL7343120 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1NPSR1KMT2A | |
| SCHEMBL6773935 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BKMT2AMEN1GPR139 | |
| SCHEMBL6777472 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BKMT2AMEN1GPR139 | |
| SCHEMBL6773940 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BKMT2AMEN1GPR139 | |
| SCHEMBL6783814 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |