Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 5/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399590 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL7349047 | 0.83 | ITGB3 (0.35) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398405 | 0.82 | ITGB3 (0.43) | ITGB3ITGA2BITGAV | |
| SCHEMBL7405899 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL7406626 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL7982999 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BITGAV | |
| SCHEMBL7403718 | 0.74 | ITGB3 (0.45) | ITGB3ITGA2BITGAV | |
| SCHEMBL7405748 | 0.73 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL7402756 | 0.73 | ITGB3 (0.40) | ITGB3ITGA2BITGAV | |
| SCHEMBL7404005 | 0.70 | ITGB3 (0.38) | ITGB3ITGA2BITGAVMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |