Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843336 | 0.86 | PGR (0.69) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL6843333 | 0.86 | PGR (0.69) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL8396014 | 0.84 | PGR (0.66) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL19628769 | 0.84 | PGR (0.66) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL11326826 | 0.84 | PGR (0.66) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL10897035 | 0.83 | PGR (0.67) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL23638424 | 0.83 | PGR (0.67) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL19625918 | 0.83 | PGR (0.67) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL19625822 | 0.83 | PGR (0.67) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL6510758 | 0.82 | PGR (0.64) | PGRCYP3A4ALDH1A1CYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973791-A2 | PROCESS FOR PREPARATION OF 7 ALPHA-CARBOXYL 9, 11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. Searle & Co. (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1997021720-A2 | PROCESSES FOR PREPARATION OF 7 ALPHA-CARBOXYL 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN AND A GENERAL PROCESS FOR THE EPOXIDATION OF OLIFINIC DOUBLE BONDS | G.D. SEARLE AND CO. (US) | 1997-06-19 | — | — | WO | claimed |