Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377152 | 0.81 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL1991927 | 0.80 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4PRCP | |
| SCHEMBL2415851 | 0.80 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4PRCP | |
| SCHEMBL1993835 | 0.80 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4PRCP | |
| SCHEMBL4724631 | 0.79 | PRCP (0.46) | PRCP | |
| SCHEMBL5892835 | 0.78 | HDAC8 (0.32) | CHRNB2CHRNA7CHRNA4PRCP | |
| SCHEMBL2628904 | 0.77 | — | — | |
| SCHEMBL19943585 | 0.77 | — | — | |
| SCHEMBL26495534 | 0.77 | — | — | |
| SCHEMBL19996549 | 0.77 | PRCP (0.45) | CHRNB2CHRNA7CHRNA4PRCPAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923563-A1 | 1,4-HETEROCYCLIC METALLPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008825-A1 | 1,4-HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |