Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 1.00 |
| ▸ | ACE | P12821 | 12/20 | 1.00 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349685 | 1.00 | MME (1.00) | MMEACEXIAP | |
| SCHEMBL7440414 | 0.90 | ACE (1.00) | MMEACE | |
| SCHEMBL7341603 | 0.90 | ACE (1.00) | MMEACE | |
| SCHEMBL7341608 | 0.90 | ACE (1.00) | MMEACE | |
| SCHEMBL7440402 | 0.90 | ACE (1.00) | MMEACE | |
| SCHEMBL7350620 | 0.81 | MME (1.00) | MMEACEXIAP | |
| SCHEMBL7346952 | 0.81 | MME (1.00) | MMEACEXIAP | |
| SCHEMBL8799942 | 0.81 | MME (0.70) | MMEACEXIAP | |
| SCHEMBL8837702 | 0.80 | ACE (0.67) | MMEACEXIAP | |
| SCHEMBL7437956 | 0.79 | ACE (1.00) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654294-A | CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646276-A | ANGIOTENSIN CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE INHIBITORS; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5552397-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0599444-A1 | Dual action inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1994-06-01 | — | — | EP | disclosed |