Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351705 | 0.87 | AVPR2 (0.52) | AVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7383366 | 0.86 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL8557550 | 0.83 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL7355568 | 0.83 | ACHE (0.54) | AVPR2AVPR1A | |
| SCHEMBL7351890 | 0.82 | AVPR1A (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL7335096 | 0.81 | AVPR2 (0.82) | AVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7350665 | 0.81 | AVPR1A (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL7352577 | 0.80 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL7344384 | 0.80 | AVPR1A (0.63) | AVPR2AVPR1AOXTR | |
| Hydrochloric Acid SCHEMBL7354212 | 0.79 | AVPR1A (0.62) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5504085-A | TREATING ISCHEMIA, ANOXIA, HYPOGLYCEMIA AND HEAD, SPINAL CORD TRAUMA | NOVO NORDISK A/S (DK) | 1996-04-02 | — | — | US | disclosed |
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |