Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.55 |
| ▸ | PDE4A | P27815 | 9/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350382 | 0.90 | PDE4D (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7348827 | 0.89 | PDE4D (0.52) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7415300 | 0.88 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29240090 | 0.78 | PDE4D (0.53) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29240088 | 0.77 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7420808 | 0.77 | PDE4D (0.66) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL5038816 | 0.77 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7355475 | 0.76 | PDE4B (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7417119 | 0.76 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30063786 | 0.76 | PDE4B (0.55) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015045-A1 | N-(3-PHENYLPROPYL)OXAMIC ACID, OXAMATE, AND OXAMIDE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-05 | — | — | WO | claimed |
| WO-1993015045-A1 | N-(3-PHENYLPROPYL)OXAMIC ACID, OXAMATE, AND OXAMIDE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-08-05 | — | — | WO | disclosed |