Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7350484 | 1.00 | KHK (0.36) | KHKMAOBSFRP1PIM1PIM2 | |
| SCHEMBL7371541 | 0.82 | KHK (0.38) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL7371548 | 0.82 | KHK (0.38) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL7345541 | 0.80 | MAOB (0.37) | MAOB | |
| SCHEMBL7374491 | 0.80 | KHK (0.41) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL7374493 | 0.80 | KHK (0.41) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL8817959 | 0.80 | KHK (0.41) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL8819354 | 0.80 | KHK (0.38) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL8819369 | 0.80 | KHK (0.38) | KHKMAOBPIM1PIM2HDAC1 | |
| SCHEMBL8820177 | 0.80 | KHK (0.38) | KHKMAOBPIM1PIM2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912555-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049699-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |