Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353205 | 0.95 | GPR119 (0.43) | MAOBGPR119CYP3A4CYP2C9 | |
| SCHEMBL27498541 | 0.95 | MAOB (0.34) | MAOBGPR119CREBBPCYP3A4WNT1 | |
| SCHEMBL7350998 | 0.84 | GPR119 (0.39) | GPR119CREBBPCYP3A4WNT1GSK3B | |
| SCHEMBL7351896 | 0.82 | GPR119 (0.37) | MAOBGPR119CYP3A4CNR1 | |
| SCHEMBL7412242 | 0.82 | GPR119 (0.37) | MAOBGPR119CYP3A4CNR1 | |
| SCHEMBL27497196 | 0.81 | MAOB (0.34) | MAOBCREBBPWNT1GSK3BDYRK1A | |
| SCHEMBL7350814 | 0.81 | GPR119 (0.40) | GPR119CYP3A4WNT1GSK3BDYRK1A | |
| SCHEMBL7350819 | 0.81 | GPR119 (0.40) | GPR119CYP3A4WNT1GSK3BDYRK1A | |
| Trifluoroacetic Acid SCHEMBL7350484 | 0.80 | KHK (0.36) | MAOB | |
| Trifluoroacetic Acid SCHEMBL7350478 | 0.80 | KHK (0.36) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912555-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049699-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |