Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342791 | 0.93 | LTA4H (0.52) | LTA4HMAPTLMNATDP1PPID | |
| SCHEMBL6286612 | 0.81 | LTA4H (0.47) | LTA4HMAPT | |
| Hydrochloric Acid SCHEMBL5174869 | 0.80 | LTA4H (0.46) | LTA4HMAPT | |
| SCHEMBL15441059 | 0.79 | HDAC8 (0.52) | HDAC8MAPTLMNATDP1CA1 | |
| SCHEMBL15890597 | 0.79 | CYP17A1 (0.52) | LTA4HMAPTTDP1HDAC1HDAC6 | |
| SCHEMBL7351394 | 0.74 | MAPT (0.44) | HDAC8MAPTLMNATDP1CA1 | |
| SCHEMBL17978114 | 0.74 | SLC7A5 (0.45) | LTA4HLMNAPPARGPPARA | |
| SCHEMBL17978113 | 0.74 | SLC7A5 (0.45) | LTA4HLMNAPPARGPPARA | |
| SCHEMBL29714948 | 0.74 | HDAC8 (0.59) | HDAC8CA1CA2HDAC3HDAC4 | |
| SCHEMBL30519915 | 0.74 | TP53 (0.54) | LTA4HHDAC8MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907637-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000395-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 1998-01-08 | — | — | WO | disclosed |