Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.57 |
| ▸ | F10 | P00742 | 10/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7360424 | 0.90 | F2 (0.55) | F2F10ITGB3ITGA2BGAA | |
| SCHEMBL7353216 | 0.90 | F2 (0.58) | F2F10ITGB3ITGA2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7356248 | 0.86 | F2 (0.54) | F2F10GAATSHRST14 | |
| Iodide SCHEMBL7357519 | 0.85 | F2 (0.55) | F2F10ITGB3ITGA2BSMN1; SMN2 | |
| Iodide SCHEMBL7362204 | 0.83 | F2 (0.56) | F2F10SMN1; SMN2GAATSHR | |
| SCHEMBL6639091 | 0.81 | F2 (0.84) | F2SMN1; SMN2GAATSHRST14 | |
| Hydrochloric Acid SCHEMBL7361185 | 0.81 | F2 (0.66) | F2F10 | |
| SCHEMBL7356550 | 0.81 | F2 (0.47) | F2SMN1; SMN2GAATSHR | |
| SCHEMBL7355195 | 0.81 | F2 (0.42) | F2SMN1; SMN2GAATSHR | |
| Hydrochloric Acid SCHEMBL7358813 | 0.81 | F2 (0.52) | F2F10GAATSHRST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |