Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356407 | 0.90 | ALDH1A1 (0.44) | F2FNTAFNTBPGGT1BGAA | |
| Hydrochloric Acid SCHEMBL7360424 | 0.88 | F2 (0.55) | F2GAATSHRALDH1A1PKM | |
| SCHEMBL7351436 | 0.85 | F2 (0.44) | F2FNTAFNTBPGGT1BGAA | |
| SCHEMBL7355762 | 0.83 | HCRTR2 (0.36) | F2FNTAFNTBPTPN2PTPN1 | |
| SCHEMBL7353216 | 0.82 | F2 (0.58) | F2GAATSHRALDH1A1PKM | |
| SCHEMBL8026776 | 0.82 | F2 (0.49) | F2FNTAFNTBPGGT1BGAA | |
| SCHEMBL8138889 | 0.81 | F2 (0.64) | F2FNTAFNTBPGGT1BGAA | |
| SCHEMBL6635727 | 0.81 | F2 (0.49) | F2FNTAFNTBPGGT1BGAA | |
| SCHEMBL7981133 | 0.81 | F2 (0.53) | F2FNTAFNTBPGGT1BGAA | |
| SCHEMBL6638786 | 0.81 | F2 (0.65) | F2FNTAFNTBPGGT1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |