Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036449 | 0.74 | KMT2A (0.43) | SLC1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21243694 | 0.71 | HCAR2 (0.43) | SLC1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28536954 | 0.71 | MGAM (0.52) | MGAMGAASIMGAM2CHRM2 | |
| SCHEMBL6033533 | 0.71 | MGAM (0.43) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL1403558 | 0.70 | TSHR (0.36) | SLC1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7341660 | 0.69 | NOTUM (0.43) | KMT2AALDH1A1 | |
| SCHEMBL406639 | 0.69 | CHRM2 (0.34) | SLC1A2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8751786 | 0.68 | MGAM (0.55) | MGAMGAASIMGAM2CHRM2 | |
| SCHEMBL182320 | 0.68 | MGAM (0.55) | MGAMGAASIMGAM2CHRM2 | |
| SCHEMBL6837511 | 0.68 | MGAM (0.55) | MGAMGAASIMGAM2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |