SCHEMBL7352143

SCHEMBL7352143

COC(=O)c1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
BACE1 P56817 1/20 0.50
NR1H2 P55055 1/20 0.50
NAMPT P43490 1/20 0.50
ACHE P22303 1/20 0.49
POLB P06746 1/20 0.49
GPR119 Q8TDV5 1/20 0.49
SMARCA2 P51531 1/20 0.48
SMARCA4 P51532 1/20 0.48
PBRM1 Q86U86 1/20 0.48
CKS1B P61024 1/20 0.48
SKP1 P63208 1/20 0.48
SKP2 Q13309 1/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MYC P01106 1/20 0.48
PTPN11 Q06124 1/20 0.47
EED O75530 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502254 0.88 SMARCA2 (0.48) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL22835677 0.88 SMARCA2 (0.48) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL29627893 0.87 KMT2A (0.51) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL20516391 0.87 POLB (0.51) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL25024079 0.87 KMT2A (0.51) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL22835372 0.86 BACE1 (0.46) KMT2AL3MBTL1BACE1NR1H2NAMPT
SCHEMBL110679 0.86 GPR119 (0.54) KMT2ABACE1NAMPTACHEPOLB
SCHEMBL2327346 0.86 GPR119 (0.51) BACE1NAMPTPOLBGPR119SMARCA2
SCHEMBL14598744 0.86 GAA (0.59) KMT2AACHEPOLBGPR119CKS1B
SCHEMBL21360304 0.85 BACE1 (0.54) KMT2ABACE1NAMPTACHEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US disclosed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP disclosed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN disclosed
US-5932582-A Fibrinogen receptor antagonist prodrugs MERCK & CO., INC. (US) 1999-08-03 US disclosed
EP-0912513-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS Merck & Co., Inc. (US) 1999-05-06 EP disclosed
WO-1998000401-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS MERCK & CO., INC. (US) 1998-01-08 WO disclosed