Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342224 | 0.90 | HSD17B10 (0.65) | HSD17B10CACNA1BADORA3MEN1KMT2A | |
| SCHEMBL7342453 | 0.89 | CACNA1F (0.63) | HSD17B10ADORA3MEN1KMT2ACACNA1F | |
| SCHEMBL7340104 | 0.89 | HSD17B10 (0.63) | HSD17B10CACNA1BADORA3MEN1KMT2A | |
| SCHEMBL7350786 | 0.89 | HSD17B10 (0.63) | HSD17B10CACNA1BADORA3MEN1KMT2A | |
| SCHEMBL7349033 | 0.88 | CACNA1F (0.65) | HSD17B10ADORA3MEN1KMT2ACACNA1F | |
| SCHEMBL7349495 | 0.86 | CACNA1F (0.65) | HSD17B10ADORA3MEN1KMT2ACACNA1F | |
| SCHEMBL10918103 | 0.85 | MAPT (0.70) | ADORA3MEN1KMT2ACACNA1FCACNA1D | |
| SCHEMBL7350843 | 0.85 | MAPT (0.70) | ADORA3MEN1KMT2ACACNA1FCACNA1D | |
| SCHEMBL7342557 | 0.83 | HSD17B10 (0.66) | HSD17B10CACNA1BADORA3MEN1KMT2A | |
| SCHEMBL7349681 | 0.83 | HSD17B10 (0.56) | HSD17B10CACNA1BADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833150-A | HYPOTENSIVES, ANTIARRHYTHMIA AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4652573-A | HYPOTENSIVE AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0194685-A1 | 1,4-Dihydropyridines | Whitby Research Incorporated (US) | 1986-09-17 | — | — | EP | disclosed |