Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747146 | 1.00 | TDP1 (0.50) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL30192877 | 0.82 | TDP1 (0.49) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL1547216 | 0.82 | TDP1 (0.49) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL5431900 | 0.82 | TDP1 (0.49) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL1390651 | 0.82 | TDP1 (0.49) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL30192680 | 0.82 | TDP1 (0.49) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL11408262 | 0.82 | TDP1 (0.53) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL5421950 | 0.80 | TDP1 (0.47) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL29381145 | 0.78 | TDP1 (0.57) | TDP1LMNACASP3ALDH1A1HTT | |
| SCHEMBL6656473 | 0.78 | TDP1 (0.57) | TDP1LMNACASP3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476659-B1 | A 3(5)-Hydrazinopyrazole compound | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | claimed |
| US-5235058-A | Photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-10 | — | — | US | claimed |
| EP-0476659-B1 | A 3(5)-Hydrazinopyrazole compound | FUJI PHOTO FILM CO LTD (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5235058-A | Photographic couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0476659-A1 | A 3(5)-Hydrazinopyrazole compound | Fuji Photo Film Co., Ltd. (JP) | 1992-03-25 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |