Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 4/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277980 | 0.88 | CASP2 (0.79) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL11335765 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL12266775 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL6276593 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL1456491 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23775006 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21633848 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL21234011 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL20542645 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL22271678 | 0.86 | CASP2 (0.83) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |