Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352667 | 1.00 | F13A1 (0.43) | F13A1TGM2TSHRNT5ETAAR1 | |
| SCHEMBL7349178 | 1.00 | F13A1 (0.43) | F13A1TGM2TSHRNT5ETAAR1 | |
| SCHEMBL7349182 | 1.00 | F13A1 (0.43) | F13A1TGM2TSHRNT5ETAAR1 | |
| SCHEMBL7353601 | 0.87 | TSHR (0.45) | TSHRNT5ETAAR1LMNASLC6A2 | |
| SCHEMBL7353619 | 0.87 | TSHR (0.45) | TSHRNT5ETAAR1LMNASLC6A2 | |
| SCHEMBL7353615 | 0.87 | TSHR (0.45) | TSHRNT5ETAAR1LMNASLC6A2 | |
| SCHEMBL7353598 | 0.87 | TSHR (0.45) | TSHRNT5ETAAR1LMNASLC6A2 | |
| SCHEMBL24215035 | 0.79 | TSHR (0.61) | TSHRTAAR1LMNASLC6A2 | |
| SCHEMBL24572017 | 0.79 | TSHR (0.61) | TSHRTAAR1LMNASLC6A2 | |
| SCHEMBL13941992 | 0.79 | TSHR (0.61) | TSHRTAAR1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |