Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353601 | 1.00 | TSHR (0.45) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7353615 | 1.00 | TSHR (0.45) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7353619 | 1.00 | TSHR (0.45) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7352663 | 0.87 | F13A1 (0.43) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7349178 | 0.87 | F13A1 (0.43) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7349182 | 0.87 | F13A1 (0.43) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL7352667 | 0.87 | F13A1 (0.43) | TSHRLMNANT5ESLC6A2TACR2 | |
| SCHEMBL8723296 | 0.84 | NT5E (0.53) | NT5ETACR2 | |
| SCHEMBL21332726 | 0.82 | NT5E (0.46) | NT5ETACR2 | |
| SCHEMBL30712002 | 0.82 | NT5E (0.48) | NT5ETACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153589-A | FOR TREATING VIRAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-11-28 | — | — | US | disclosed |
| US-5190969-A | Epoxy derivatives of amino acids as viricides for treatment of HIV infections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1993-03-02 | — | — | US | disclosed |