Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.62 |
| ▸ | OXTR | P30559 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353247 | 0.91 | AVPR2 (0.53) | AVPR2AVPR1AHSD11B1HPGDALDH1A1 | |
| SCHEMBL27318182 | 0.86 | AVPR2 (0.53) | AVPR2AVPR1AOXTRHSD11B1HPGD | |
| SCHEMBL13980487 | 0.85 | AVPR2 (0.58) | AVPR2AVPR1AOXTRHSD11B1 | |
| SCHEMBL7346654 | 0.84 | MAPT (0.47) | HPGDALDH1A1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7352202 | 0.80 | AVPR2 (0.56) | AVPR2AVPR1AOXTRHSD11B1HPGD | |
| SCHEMBL27325426 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1AOXTRHSD11B1HPGD | |
| SCHEMBL7357354 | 0.78 | AVPR2 (0.54) | AVPR2AVPR1AOXTRHSD11B1HPGD | |
| SCHEMBL7347092 | 0.77 | AVPR2 (1.00) | AVPR2AVPR1AOXTRALDH1A1CA1 | |
| SCHEMBL26938797 | 0.76 | MAPT (0.46) | ALDH1A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7355733 | 0.76 | AVPR1A (0.60) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048484-C | A process for preparing a composition containing benzoheterocycles | OTSUKA PHARMA CO LTD (JP) | 2000-01-19 | — | — | CN | disclosed |
| US-5985869-A | USEFUL AS VASODILATORS, HYPOTENSIVE AGENTS, WATER DIURETICS, PLATELET AGGLUTINATION INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5559230-A | VASOPRESSIN ANTAGONISTS, QUINOLINES, BENZAZEPINES, VASODILATION, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0450097-B1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| CN-1027505-C | Process for preparing benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 1995-01-25 | — | — | CN | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |