Butyric Acid

Butyric Acid

SCHEMBL7353262

CCCC(=O)O.CCCCCCCC(CC)C(=O)O

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.68
MAPK1 P28482 1/20 0.68
FFAR4 Q5NUL3 2/20 0.55
FFAR1 O14842 2/20 0.55
GRIK1 P39086 2/20 0.54
GRIK2 Q13002 2/20 0.54
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL7866431 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL3040683 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL2898631 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL4739546 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL4740443 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL2683595 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL2898496 1.00 CA2 (0.68) CA2MAPK1FFAR4FFAR1GRIK1
Butyric Acid SCHEMBL8469380 0.98 CA2 (0.70) CA2MAPK1FFAR4FFAR1GRIK1
2-Ethylhexanoic Acid SCHEMBL10545013 0.93 CA2 (0.69) CA2MAPK1FFAR4FFAR1GPR84
Undecanoate SCHEMBL9955968 0.93 CA2 (0.68) CA2MAPK1FFAR4FFAR1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5972963-A AN ANTIDEPRESSANT, MODULATORS OF NEUROTRANSMITTER FUNCTION SUCH AS SEROTONERGIC AND ADRENERGIC, DOPAMINERGIC AGENTS HOECHST MARION ROUSSEL, INC. (US) 1999-10-26 US disclosed