Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSH | P09668 | 2/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527881 | 0.86 | CTSK (0.65) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7417702 | 0.86 | CTSK (0.65) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7732224 | 0.85 | CTSK (0.63) | CTSKCTSBCTSLCTRB1 | |
| SCHEMBL18857044 | 0.85 | SMN1; SMN2 (0.62) | CTSLATM | |
| SCHEMBL5275940 | 0.85 | CTSK (0.59) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL30825010 | 0.85 | CTSK (0.59) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL5275932 | 0.85 | CTSK (0.59) | CTSKCTSBCTSLCTSHPSMB1 | |
| SCHEMBL5674735 | 0.84 | CTSK (0.77) | CTSKCTSBCTSLCTSH | |
| SCHEMBL5674738 | 0.84 | CTSK (0.77) | CTSKCTSBCTSLCTSH | |
| SCHEMBL16230129 | 0.84 | CTSK (0.56) | CTSKCTSBCTSLCTSHPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |