Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.68 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452873 | 1.00 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL11768331 | 0.93 | MAPT (0.78) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL10672992 | 0.89 | KMT2A (0.65) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL10672989 | 0.89 | KMT2A (0.65) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL10756378 | 0.89 | KMT2A (0.86) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL10756388 | 0.89 | KMT2A (0.86) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL15026368 | 0.89 | KMT2A (0.86) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL10570850 | 0.86 | LMNA (0.57) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL16672718 | 0.85 | LMNA (0.58) | MEN1KMT2AMAPTLMNAPLIN1 | |
| SCHEMBL11547965 | 0.85 | MEN1 (0.63) | MEN1KMT2AMAPTLMNAPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898877-A | ANTIARRHYTHMIA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |
| EP-0280992-A1 | Cyclohexene carboxylic-acid esters, process for their preparation and their use | BAYER AG (DE) | 1988-09-07 | — | — | EP | disclosed |