Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.55 |
| ▸ | NPY1R | P25929 | 10/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.55 |
| ▸ | NPY2R | P49146 | 6/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350041 | 0.92 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29602482 | 0.90 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30092991 | 0.87 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RF2 | |
| SCHEMBL9755304 | 0.85 | NPY4R (0.72) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9755302 | 0.85 | NPY4R (0.72) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30092922 | 0.85 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RF2 | |
| SCHEMBL29521070 | 0.84 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9141613 | 0.84 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29617176 | 0.84 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RF2 | |
| SCHEMBL29539204 | 0.84 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561876-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF ATHEROMA. | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561878-A1 | USE OF ANGIOTENSIN II ANTAGONIST IN THE TREATMENT OF INFARCTION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561896-A1 | USE OF ANGIOTENSN II RECEPTOR ANTAGONISTS FOR THE PREPARATION OF A MEDICAMENT FOR IMPROVING COGNITIVE FUNCTION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561905-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF MACULAR DEGENERATION | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0561979-A1 | USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF ANGINA PECTORIS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010187-A1 | USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF ANGINA PECTORIS | SMITHKLINE BEECHAM PLC (GB) | 1992-06-25 | — | — | WO | disclosed |