SCHEMBL29602482

SCHEMBL29602482

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.59
▸ NPY1R P25929 9/20 0.59
▸ NPY5R Q15761 8/20 0.59
▸ NPY2R P49146 5/20 0.59
▸ KISS1R Q969F8 2/20 0.49
▸ OPRD1 P41143 1/20 0.48
▸ AGTR1 P30556 1/20 0.48
▸ AGTR2 P50052 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755306 0.93 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL9755301 0.93 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29649760 0.92 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL29649734 0.92 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL29611423 0.92 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL7353834 0.90 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29779431 0.90 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL29580583 0.90 VIPR2 (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL7350041 0.89 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31195744 0.89 KISS1R (0.59) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022094025-A1 ANGIOTENSIN-1-7 FOR THE TREATMENT OF COVID-19 DIZEREGA GERE (US) 2022-05-05 — — WO claimed
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 — — US disclosed
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease Capacity Bio, Inc. (US) 2025-07-01 — — US disclosed
CN-119574244-A Human angiotensin II purity standard substance and preparation method and application thereof 广东省计量科学研究院(华南国家计量测试中心) 2025-03-07 — — CN disclosed
EP-4371556-A1 ANGIOTENSIN(1-7) PHARMACEUTICAL COMPOSITIONS FOR INHALATION Explicat Pharma GmbH (DE) 2024-05-22 — — EP disclosed
US-20220243210-A1 ANGIOTENSIN II TYPE 1 RECEPTOR TARGETED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2022-08-04 — — US disclosed
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. 2022-07-28 — — US disclosed
WO-2022094025-A1 ANGIOTENSIN-1-7 FOR THE TREATMENT OF COVID-19 DIZEREGA GERE (US) 2022-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12343331-B2 Methods and agents that stimulate mitochondrial turnover for treating disease NLN, MAVS, PINK1 NPY4R 295/4885NPY1R 176/4885NPY5R 334/4885
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE NLN, MAVS, PINK1 NPY4R 295/4885NPY1R 176/4885NPY5R 334/4885
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE MDH2, NLN, PINK1 NPY4R 1830/4885NPY1R 504/4885NPY5R 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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