Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353835 | 0.96 | CACNA1B (0.42) | CACNA1BMCHR1 | |
| SCHEMBL7350736 | 0.92 | CACNA1B (0.42) | CACNA1BCHRM1HTR2A | |
| SCHEMBL7356277 | 0.91 | CACNA1B (0.51) | CACNA1BHSD17B10 | |
| SCHEMBL7351806 | 0.91 | CACNA1B (0.45) | CACNA1B | |
| SCHEMBL7359802 | 0.89 | CACNA1B (0.42) | CACNA1B | |
| SCHEMBL7349827 | 0.89 | CACNA1B (0.42) | CACNA1B | |
| SCHEMBL7353830 | 0.88 | CACNA1B (0.50) | CACNA1BCHRM1 | |
| SCHEMBL7360274 | 0.87 | CACNA1B (0.42) | CACNA1BHTR2A | |
| SCHEMBL7042887 | 0.87 | CACNA1B (0.45) | CACNA1BHSD17B10GAACHRM1HTR2A | |
| SCHEMBL7359757 | 0.87 | MCHR1 (0.35) | CACNA1BHSD17B10GAADPP7CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |