Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CHIT1 | Q13231 | 6/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353642 | 0.96 | CHIT1 (0.37) | MCHR1CHIT1CHIAKCNH2CACNA1B | |
| SCHEMBL7357693 | 0.91 | CHIT1 (0.38) | CHIT1CHIAKCNH2CACNA1BSIGMAR1 | |
| SCHEMBL7354629 | 0.89 | CACNA1B (0.37) | CACNA1B | |
| SCHEMBL7349373 | 0.89 | CACNA1B (0.39) | CACNA1B | |
| SCHEMBL7354492 | 0.87 | CACNA1B (0.42) | MCHR1CHRM1HTR2ACACNA1BGAA | |
| SCHEMBL7045080 | 0.86 | CACNA1B (0.37) | MCHR1CHRM1HTR2ACHIT1CHIA | |
| SCHEMBL7045078 | 0.86 | CACNA1B (0.37) | MCHR1CHRM1HTR2ACHIT1CHIA | |
| SCHEMBL7349945 | 0.84 | CACNA1B (0.40) | CACNA1B | |
| SCHEMBL7354253 | 0.83 | CACNA1B (0.43) | CHRM1HTR2AKCNH2CACNA1BSIGMAR1 | |
| SCHEMBL7353835 | 0.83 | CACNA1B (0.42) | MCHR1CHIT1CHIAKCNH2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | claimed |