⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131630 | 0.93 | — | — | |
| SCHEMBL22604909 | 0.87 | — | — | |
| SCHEMBL7356603 | 0.87 | — | — | |
| SCHEMBL6652100 | 0.82 | — | — | |
| SCHEMBL10497146 | 0.82 | — | — | |
| SCHEMBL13970551 | 0.80 | — | — | |
| SCHEMBL28363666 | 0.80 | — | — | |
| Sulfuric Acid SCHEMBL7874120 | 0.80 | TP53 (0.37) | — | |
| SCHEMBL14830867 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL28363664 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274721-B1 | POLYMERS CONTAINING AMINO GROUPS, THEIR MANUFACTURE AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0543936-A4 | RENIN INHIBITORS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0543936-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003429-A1 | RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4882391-A | ELECTRODIP COATING | HOECHST AG (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0274721-A2 | Polymers containing amino groups, their manufacture and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-20 | — | — | EP | disclosed |
| EP-0047228-B1 | MIXTURES FOR THE PREPARATION OF NITROGEN-CONTAINING ADDITION POLYMERS | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4383107-A | POLYTRIAZINES; CURABLE; CASTINGS; ADHESIVES; FOAMS | CIBA-GEIGY CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |
| EP-0047228-A2 | Mixtures for the preparation of nitrogen-containing addition polymers | CIBA-GEIGY AG (CH) | 1982-03-10 | — | — | EP | disclosed |