Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327196 | 0.84 | ALDH1A1 (0.65) | PTGS1PPARAALDH1A1PPARGPPARD | |
| Pentachlorophenol SCHEMBL7355120 | 0.81 | PPARA (0.61) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL27914118 | 0.81 | ALDH1A1 (0.62) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL4211358 | 0.81 | ALDH1A1 (0.60) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL28123610 | 0.81 | PTGS1 (0.60) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL30464883 | 0.80 | PPARA (0.72) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL7359872 | 0.80 | PPARA (0.72) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL20723796 | 0.79 | PTGS1 (0.64) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL2359864 | 0.79 | PTGS1 (0.56) | PTGS1PPARAALDH1A1PPARGPPARD | |
| SCHEMBL20739834 | 0.78 | MEN1 (0.68) | PTGS1PPARAALDH1A1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032600-A | Antiarrhythmia | ALKALOIDA VEGYESZETI GYAR (HU) | 1991-07-16 | — | — | US | disclosed |
| US-5028609-A | Antiarrhythmia agents | ALKALOIDA VEGYESZETI GYAR (HU) | 1991-07-02 | — | — | US | disclosed |
| US-4897413-A | ANTIARRHYTHMIA AGENTS | ALKALOIDA VEGYESZETI GYAR (HU) | 1990-01-30 | — | — | US | disclosed |
| EP-0134225-B1 | NEW ALKYL DIAMINE DERIVATIVES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-08-17 | — | — | EP | disclosed |
| US-4703056-A | ANTIARRHYTHMIA AGENTS | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-10-27 | — | — | US | disclosed |
| EP-0134225-A1 | NEW ALKYL DIAMINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1985-03-20 | — | — | EP | disclosed |
| WO-1984002907-A1 | NEW ALKYL DIAMINE DERIVATIVES | ALKALOIDA VEGYESZETI GYAR (HU) | 1984-08-02 | — | — | WO | disclosed |