Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562531 | 0.89 | MAPT (0.46) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL7299483 | 0.89 | MAPT (0.46) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL1638984 | 0.85 | MAPT (0.54) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10465231 | 0.83 | LMNA (0.46) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10465232 | 0.83 | LMNA (0.46) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10464825 | 0.82 | LMNA (0.45) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10464826 | 0.82 | LMNA (0.45) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10757251 | 0.82 | MAPT (0.53) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10463518 | 0.81 | LMNA (0.44) | MAPTLMNANPY1RNPY2RKMT2A | |
| SCHEMBL10463519 | 0.81 | LMNA (0.44) | MAPTLMNANPY1RNPY2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287866-A1 | Substituted 1,4-dihydropyridines, method for their preparation and their use | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |