Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293331 | 0.82 | MEN1 (0.36) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL631310 | 0.81 | — | — | |
| SCHEMBL27237566 | 0.79 | MEN1 (0.38) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL27823981 | 0.74 | LMNA (0.32) | CYP3A4LMNA | |
| SCHEMBL9438260 | 0.74 | MEN1 (0.33) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL28049474 | 0.73 | TSHR (0.39) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL1971821 | 0.73 | — | — | |
| SCHEMBL29145068 | 0.72 | MEN1 (0.32) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL16774630 | 0.70 | TSHR (0.33) | LMNA | |
| SCHEMBL598505 | 0.70 | TSHR (0.32) | MEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722321-A4 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0722321-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009620-A1 | SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |