Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.79 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346572 | 0.90 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7353828 | 0.90 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7347039 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL7350314 | 0.86 | ITGB3 (0.70) | ITGB3ITGA2B | |
| SCHEMBL7346651 | 0.86 | ITGB3 (0.77) | ITGB3ITGA2B | |
| SCHEMBL7351416 | 0.85 | ITGB3 (0.81) | ITGB3ITGA2B | |
| Xemilofiban SCHEMBL50663 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Xemilofiban SCHEMBL5163315 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Xemilofiban SCHEMBL609244 | 0.84 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7347420 | 0.84 | ITGB3 (0.73) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542708-B1 | Substituted beta-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2001-05-30 | — | — | EP | disclosed |
| US-5973003-A | TREATMENT OF THROMBOSIS, STROKE, MYOCARDIAL INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS | G. D. SEARLE & CO. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0614360-B1 | SUBSTITUTED BETA-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0614360-A1 | SUBSTITUTED -g(b)-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0542708-A1 | Substituted B-amino acid derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993007867-A1 | SUBSTITUTED β-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |