Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260009 | 1.00 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7355992 | 1.00 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9260012 | 1.00 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7673656 | 0.87 | SLC6A3 (0.68) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9257274 | 0.86 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9257271 | 0.86 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7664902 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7665291 | 0.86 | SLC6A2 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7354042 | 0.85 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7363266 | 0.85 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756596-B1 | TROPANE-2-ALDOXIME DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2002-08-21 | — | — | EP | disclosed |
| US-5736556-A | PARKINSON*S DISEASE; ANTIDEPRESSANTS; ANTIOBESITY; ANTINARCOLEPSY; DRUG ABRUSE | NEUROSEARCH A/S (DK) | 1998-04-07 | — | — | US | disclosed |
| EP-0756596-A1 | TROPANE-2-ALDOXIME DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1997-02-05 | — | — | EP | disclosed |
| WO-1995028401-A1 | TROPANE-2-ALDOXINE DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1995-10-26 | — | — | WO | disclosed |