Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.70 |
| ▸ | ITGAV | P06756 | 20/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985892 | 0.95 | ITGAV (0.78) | ITGB3ITGAVITGA2B | |
| SCHEMBL7347222 | 0.94 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL7349313 | 0.91 | ITGAV (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7353336 | 0.91 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL7985900 | 0.90 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL7352205 | 0.89 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7985881 | 0.87 | ITGB3 (0.91) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969149 | 0.85 | ITGB3 (0.91) | ITGB3ITGAVITGA2B | |
| SCHEMBL7986095 | 0.85 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979430 | 0.83 | ITGB3 (0.90) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |